Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 17/20 | 0.54 |
| ▸ | HRH1 | P35367 | 17/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966022 | 1.00 | HRH2 (0.54) | HRH2HRH1RAB9AHRH3KDM4E | |
| SCHEMBL7979503 | 0.89 | HRH2 (0.58) | HRH2HRH1HRH3KDM4EDRD2 | |
| SCHEMBL7966211 | 0.89 | HRH2 (0.58) | HRH2HRH1HRH3KDM4EDRD2 | |
| SCHEMBL7979778 | 0.85 | HRH1 (0.61) | HRH2HRH1HRH3 | |
| SCHEMBL7982418 | 0.81 | HRH3 (0.47) | HRH2HRH1HRH3 | |
| SCHEMBL7250885 | 0.80 | HRH2 (0.71) | HRH2HRH1RAB9AHRH3DRD2 | |
| SCHEMBL7244819 | 0.80 | HRH2 (0.71) | HRH2HRH1RAB9AHRH3DRD2 | |
| SCHEMBL7976330 | 0.80 | HRH2 (0.71) | HRH2HRH1RAB9AHRH3DRD2 | |
| SCHEMBL7245178 | 0.79 | HRH2 (0.61) | HRH2HRH1RAB9AHRH3KDM4E | |
| SCHEMBL7978302 | 0.79 | HRH2 (0.61) | HRH2HRH1RAB9AHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |