Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.61 |
| ▸ | HRH2 | P25021 | 16/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245055 | 0.88 | HRH1 (0.64) | HRH1HRH2HRH3KCNA5 | |
| SCHEMBL7966022 | 0.85 | HRH2 (0.54) | HRH1HRH2HRH3 | |
| SCHEMBL7966042 | 0.85 | HRH2 (0.54) | HRH1HRH2HRH3 | |
| SCHEMBL7966211 | 0.85 | HRH2 (0.58) | HRH1HRH2HRH3 | |
| SCHEMBL7979503 | 0.85 | HRH2 (0.58) | HRH1HRH2HRH3 | |
| SCHEMBL7245429 | 0.83 | KCNA5 (0.57) | HRH1HRH2HRH3KCNA5 | |
| SCHEMBL7242852 | 0.82 | HRH1 (0.70) | HRH1HRH2HRH3 | |
| SCHEMBL7250960 | 0.81 | HRH2 (0.68) | HRH1HRH2HRH3KCNA5 | |
| SCHEMBL7246489 | 0.81 | HRH2 (0.68) | HRH1HRH2HRH3KCNA5 | |
| SCHEMBL7248885 | 0.81 | HRH1 (0.67) | HRH1HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |