Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.76 |
| ▸ | PTGER3 | P43115 | 13/20 | 0.76 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.76 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957258 | 1.00 | PTGER4 (0.76) | PTGER4PTGER3PTGER2PTGER1ALDH1A1 | |
| SCHEMBL7805023 | 0.86 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7805026 | 0.86 | PTGER2 (1.00) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7966426 | 0.79 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7966425 | 0.79 | PTGER4 (0.82) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7804187 | 0.77 | PTGER2 (0.83) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7804194 | 0.77 | PTGER2 (0.83) | PTGER4PTGER3PTGER2PTGER1KMT2A | |
| SCHEMBL7957266 | 0.77 | PTGER4 (0.70) | PTGER4PTGER3PTGER2PTGER1ALDH1A1 | |
| SCHEMBL18802206 | 0.75 | NFE2L2 (0.50) | PTGER4PTGER3PTGER2ALDH1A1MAPT | |
| SCHEMBL1157798 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |