Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966464 | 1.00 | KDM4E (0.63) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1481794 | 0.94 | POLB (0.59) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1481792 | 0.94 | POLB (0.59) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7956711 | 0.92 | POLB (0.56) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7956707 | 0.92 | POLB (0.56) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7969916 | 0.90 | PLA2G4A (0.57) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7969930 | 0.90 | PLA2G4A (0.57) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7209884 | 0.90 | PLA2G4A (0.57) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7970622 | 0.90 | PLA2G4A (0.57) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7969907 | 0.90 | PLA2G4A (0.57) | KDM4EPOLBALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213053-C | Photocrosslinkable silane derivatives | ROLIC AG (CH) | 2005-08-03 | — | — | CN | disclosed |
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |
| CN-1195015-A | Photocrosslinkable silane derivatives | ROLIC AG (CH) | 1998-10-07 | — | — | CN | disclosed |