Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 3/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7964988 | 0.99 | MAP3K7 (0.33) | MAP3K7GRM7KMT2AAVPR2AVPR1A | |
| SCHEMBL7966521 | 0.93 | MAP3K7 (0.33) | MAP3K7GRM7KMT2AABCB1CYP3A4 | |
| SCHEMBL7965069 | 0.92 | LMNA (0.36) | MAP3K7AVPR2AVPR1AAVPR1BMAPT | |
| Hydrochloric Acid SCHEMBL7966276 | 0.92 | LMNA (0.36) | MAP3K7AVPR2AVPR1AAVPR1BMAPT | |
| SCHEMBL7955268 | 0.91 | AVPR2 (0.33) | MAP3K7AVPR2AVPR1AAVPR1BMAPT | |
| SCHEMBL7480849 | 0.91 | AVPR2 (0.35) | MAP3K7KMT2AAVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7975512 | 0.91 | AVPR2 (0.32) | MAP3K7AVPR2AVPR1AAVPR1BMAPT | |
| Hydrochloric Acid SCHEMBL7481449 | 0.90 | AVPR2 (0.35) | MAP3K7AVPR2AVPR1AAVPR1BCYP3A4 | |
| SCHEMBL7964762 | 0.90 | AVPR2 (0.37) | MAP3K7KMT2AAVPR2AVPR1AAVPR1B | |
| Dimethylamine SCHEMBL7972125 | 0.90 | AVPR2 (0.35) | MAP3K7KMT2AAVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |