Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427859 | 0.88 | GPBAR1 (0.38) | CA12CA1CA2CA9ATM | |
| SCHEMBL7422214 | 0.88 | MAPT (0.43) | CA12CA1CA2CA9ATM | |
| SCHEMBL7476833 | 0.87 | ALDH1A1 (0.43) | CA12CA1CA2CA9ATM | |
| SCHEMBL7969119 | 0.81 | CA12 (0.53) | CA12CA1CA2CA9L3MBTL4 | |
| SCHEMBL7348285 | 0.81 | TP53 (0.38) | ATMDRD2STING1ALDH1A1L3MBTL1 | |
| SCHEMBL7590287 | 0.81 | MAPT (0.38) | ATMALDH1A1L3MBTL1 | |
| SCHEMBL7347816 | 0.80 | TP53 (0.38) | ATMSTING1ALDH1A1L3MBTL1 | |
| SCHEMBL7780810 | 0.80 | TP53 (0.42) | ATMDRD2L3MBTL1BRD4 | |
| SCHEMBL7345297 | 0.80 | MAPT (0.40) | ATMDRD2STING1L3MBTL1BRD4 | |
| SCHEMBL7336388 | 0.80 | TP53 (0.39) | ATMSTING1L3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |