SCHEMBL796662

SCHEMBL796662

COCCOCCOCCOc1cc(CO)cc(OCCOCCOCCOC)c1OCCOCCOCCOC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TNFRSF1A P19438 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 4/20 0.35
LMNA P02545 2/20 0.35
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
SLC6A4 P31645 1/20 0.33
PLAU P00749 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18281574 1.00 L3MBTL1 (0.37) L3MBTL1MEN1KMT2ANPC1ALOX15
SCHEMBL8208372 0.89 TUBB1 (0.36) L3MBTL1MEN1KMT2ANPC1ALOX15
SCHEMBL20339224 0.86 L3MBTL1 (0.37) L3MBTL1MEN1KMT2ANPC1TNFRSF1A
SCHEMBL18281578 0.86 L3MBTL1 (0.37) L3MBTL1MEN1KMT2ANPC1TNFRSF1A
SCHEMBL8209494 0.85 APP (0.34) MEN1KMT2ATSHRALDH1A1LMNA
SCHEMBL16232203 0.84 PTGS2 (0.46) L3MBTL1MEN1KMT2ANPC1TNFRSF1A
SCHEMBL14980569 0.84 PTGS2 (0.40) L3MBTL1MEN1KMT2ANPC1TNFRSF1A
SCHEMBL8212185 0.83 L3MBTL1 (0.40) L3MBTL1MEN1KMT2ANPC1TNFRSF1A
SCHEMBL8209889 0.82 SMN1; SMN2 (0.32) L3MBTL1ALOX15TSHRHSD17B10ALDH1A1
SCHEMBL25002434 0.80 L3MBTL1 (0.36) L3MBTL1MEN1KMT2ANPC1TNFRSF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012459-A1 SULPHIDE SENSOR OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-02-09 WO disclosed
WO-2018125524-A1 DENDRITIC LIGANDS FOR CONTROLLING SELF ASSEMBLY AND SURFACE POLARITY OF NANOPARTICLES, AND HYBRID NANOPARTICLES PRODUCED THEREFROM THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2018-07-05 WO disclosed
US-20150133653-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF PHOTOBIOTICS LIMITED (GB) 2015-05-14 US disclosed
US-20150133653-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF PHOTOBIOTICS LIMITED (GB) 2015-05-14 US disclosed
US-8404216-B2 Dendritic chelated compounds, methods for making the same and pharmaceutical compositions containing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-26 US disclosed
US-8404216-B2 Dendritic chelated compounds, methods for making the same and pharmaceutical compositions containing the same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-03-26 US disclosed
US-20120070377-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF PHOTOBIOTICS LIMITED (GB) 2012-03-22 US disclosed
US-20120070377-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF PHOTOBIOTICS LIMITED (GB) 2012-03-22 US disclosed
WO-2010106341-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF PHOTOBIOTICS LIMITED (GB) 2010-09-23 WO disclosed
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-29 US disclosed
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-29 US disclosed
WO-2008043911-A2 DENDRITIC CHELATED COMPOUNDS, METHODS FOR MAKING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133653-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF SSB, HLA-B, BDKRB1 L3MBTL1 1047/4885MEN1 516/4885KMT2A 3721/4885
US-20120070377-A1 COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF SSB, HLA-B, BDKRB1 L3MBTL1 1552/4885MEN1 507/4885KMT2A 3497/4885
US-20100104512-A1 Dendritic Chelated Compounds, Methods for Making the Same and Pharmaceutical Compositions Containing the Same ZYX, CXCR4, ZFX L3MBTL1 1695/4885MEN1 398/4885KMT2A 3370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.