Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SNCA | P37840 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP3 | P08254 | 2/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966753 | 1.00 | KDM4E (0.74) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL7970393 | 0.94 | KDM4E (0.74) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL7970389 | 0.94 | KDM4E (0.74) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL3688296 | 0.89 | KDM4E (0.77) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL30966315 | 0.89 | KDM4E (0.80) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL3690896 | 0.89 | KDM4E (0.80) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL3690899 | 0.89 | KDM4E (0.80) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL3688297 | 0.89 | KDM4E (0.77) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL7247313 | 0.85 | KDM4E (0.84) | KDM4ELMNAALDH1A1HPGDALOX15 | |
| SCHEMBL4623922 | 0.85 | KDM4E (0.84) | KDM4ELMNAALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |