Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyoxylate SCHEMBL7971642 | 0.82 | FFAR1 (0.47) | FFAR1FFAR4PTGDR2KMT2A | |
| Glyoxylate SCHEMBL7968382 | 0.82 | PTGDR2 (0.44) | PTGDR2PTGS1PPARGSMN1; SMN2MEN1 | |
| SCHEMBL12663514 | 0.78 | AKR1C3 (0.51) | KCNA5RXRAAKR1C3AKR1C2 | |
| SCHEMBL3731501 | 0.78 | FFAR1 (0.54) | FFAR1FFAR4PTGDR2PTGS1PPARG | |
| SCHEMBL31708657 | 0.78 | FFAR1 (0.45) | FFAR1FFAR4KCNA5MAPTPTGDR2 | |
| SCHEMBL5123933 | 0.77 | FFAR1 (0.49) | FFAR1FFAR4KCNA5MAPTKMT2A | |
| SCHEMBL10981131 | 0.75 | ALDH1A1 (0.49) | FFAR1FFAR4PKMMAPTPTGS1 | |
| SCHEMBL2391307 | 0.75 | FFAR1 (0.49) | FFAR1FFAR4KCNA5MAPTPTGDR2 | |
| SCHEMBL2396004 | 0.75 | FFAR1 (0.46) | FFAR1FFAR4KCNA5MAPTPTGDR2 | |
| SCHEMBL17450543 | 0.74 | FFAR4 (0.50) | FFAR1FFAR4MAPTPTGS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |