Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509941 | 0.89 | PTGDR2 (0.45) | PTGDR2ALDH1A1KMT2AFBP1MMP2 | |
| Glyoxylate SCHEMBL7971642 | 0.82 | FFAR1 (0.47) | PTGDR2KMT2APDPK1 | |
| Glyoxylate SCHEMBL7966816 | 0.82 | FFAR1 (0.47) | PTGDR2KMT2AMEN1SMN1; SMN2AKR1C3 | |
| SCHEMBL17787534 | 0.78 | S100A4 (0.40) | PTGDR2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1988581 | 0.77 | PTGDR2 (0.46) | PTGDR2ALDH1A1KMT2AMEN1AKR1C3 | |
| SCHEMBL6517710 | 0.76 | PTGDR2 (0.40) | PTGDR2ALDH1A1KDM4ESMN1; SMN2PPARG | |
| SCHEMBL17063605 | 0.76 | ESR1 (0.44) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL2395342 | 0.75 | PTGDR2 (0.43) | PTGDR2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL12798321 | 0.74 | S100A4 (0.46) | PTGDR2ALDH1A1KDM4ESMN1; SMN2PRNP | |
| SCHEMBL14825943 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |