Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.54 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 13/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273078 | 0.90 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2EPHX1TSHRALDH1A1 | |
| SCHEMBL1070119 | 0.83 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL10487232 | 0.82 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2EPHX1TSHRALDH1A1 | |
| SCHEMBL9142404 | 0.81 | ALDH1A1 (0.53) | ZDHHC20ZDHHC2EPHX1ALDH1A1GAA | |
| SCHEMBL9135855 | 0.81 | EPHX1 (0.42) | ZDHHC20ZDHHC2EPHX1GAAMEN1 | |
| SCHEMBL9142396 | 0.81 | ALDH1A1 (0.53) | ZDHHC20ZDHHC2EPHX1ALDH1A1GAA | |
| SCHEMBL6062528 | 0.79 | EPHX1 (0.48) | EPHX1TSHRALDH1A1GAAMEN1 | |
| SCHEMBL3717942 | 0.79 | EPHX1 (0.48) | EPHX1TSHRGAAMEN1KMT2A | |
| SCHEMBL1547403 | 0.79 | KDM4E (0.50) | EPHX1TSHRALDH1A1MAPK1GAA | |
| SCHEMBL19619516 | 0.79 | TSHR (0.45) | ZDHHC20ZDHHC2EPHX1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265509-B1 | POLYVINYL ACETALS | NOVARTIS AG (CH) | 2001-07-24 | — | — | US | disclosed |
| EP-0807265-B1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 2000-04-12 | — | — | EP | disclosed |
| US-5932674-A | MOLDING MATERIALS; CONTACT LENSES | NOVARTIS AG (CH) | 1999-08-03 | — | — | US | disclosed |
| EP-0807265-A1 | CROSSLINKED POLYMERS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996024074-A1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |