SCHEMBL7967005

SCHEMBL7967005

Cc1oc(C)c(N(C(=O)O)c2ccccc2)c1C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.44
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
TRPM8 Q7Z2W7 3/20 0.41
TSHR P16473 3/20 0.40
ALDH1A1 P00352 4/20 0.38
POLB P06746 2/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11840802 0.75 NPSR1 (0.42) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL17438142 0.74 KMT2A (0.51) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL9228128 0.73 KMT2A (0.54) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL9411146 0.72 MEN1 (0.35) KMT2AMEN1TDP1TRPM8HTT
SCHEMBL19778 0.72 NPSR1 (0.70) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL14740524 0.71 HPGD (0.46) NPSR1KMT2AMEN1TRPM8TSHR
Methylamine SCHEMBL10655180 0.71 NPSR1 (0.61) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL28335619 0.71 NPSR1 (0.50) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL9784470 0.70 KMT2A (0.51) NPSR1KMT2AMEN1TDP1TRPM8
SCHEMBL1081972 0.70 NPSR1 (0.41) NPSR1KMT2AMEN1TRPM8TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6199609-A None JP disclosed
US-6207692-B1 AS FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 2001-03-27 US disclosed
JP-H06199609-A USE OF FURANCARBOXYAMIDE IN PROTECTION OF MATERIAL BAYER AG 1994-07-19 JP disclosed