Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034720 | 0.74 | POLB (0.44) | NPSR1TSHRGAATRPM8KMT2A | |
| SCHEMBL1037465 | 0.71 | NPSR1 (0.41) | NPSR1TSHRGAATRPM8KMT2A | |
| SCHEMBL2344764 | 0.71 | NPC1 (0.40) | NPSR1TSHRKMT2APOLBALDH1A1 | |
| SCHEMBL7967005 | 0.70 | NPSR1 (0.44) | NPSR1TSHRTRPM8KMT2AMEN1 | |
| SCHEMBL19778 | 0.70 | NPSR1 (0.70) | NPSR1TSHRGAATRPM8KMT2A | |
| Methylamine SCHEMBL10655180 | 0.68 | NPSR1 (0.61) | NPSR1TSHRGAATRPM8KMT2A | |
| SCHEMBL28335619 | 0.68 | NPSR1 (0.50) | NPSR1TSHRTRPM8KMT2AMEN1 | |
| SCHEMBL2423771 | 0.68 | NPC1 (0.38) | NPSR1TSHRKMT2APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5094831 | 0.68 | NPSR1 (0.67) | NPSR1TSHRGAATRPM8KMT2A | |
| Bromide SCHEMBL31210017 | 0.68 | NPSR1 (0.67) | NPSR1TSHRGAATRPM8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | PFIZER INC | 2011-06-16 | — | — | US | disclosed |
| EP-2276735-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144159-A1 | ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS | FAAH, FAAH2, PAH | NPSR1 709/4885TSHR 2230/4885GPBAR1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.