SCHEMBL14740524

SCHEMBL14740524

Cc1cc(N(C(=O)O)c2ccccc2)c(C)o1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.46
NPC1 O15118 7/20 0.43
RAB9A P51151 7/20 0.43
MAPT P10636 5/20 0.43
NPSR1 Q6W5P4 3/20 0.43
LMNA P02545 1/20 0.42
ALDH1A1 P00352 4/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.41
HTT P42858 2/20 0.41
TRPM8 Q7Z2W7 1/20 0.40
MEN1 O00255 2/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
JAK2 O60674 1/20 0.38
PAX8 Q06710 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11664875 0.88 RAB9A (0.47) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL11666835 0.83 NPSR1 (0.41) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL11665876 0.81 HPGD (0.42) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL11666823 0.81 SMN1; SMN2 (0.41) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL14740532 0.80 NPSR1 (0.37) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL6398641 0.75 NPSR1 (0.44) HPGDNPC1RAB9ANPSR1ALDH1A1
SCHEMBL11741562 0.73 MAPT (0.40) HPGDNPC1RAB9AMAPTNPSR1
SCHEMBL28335619 0.73 NPSR1 (0.50) NPC1RAB9ANPSR1ALDH1A1KMT2A
SCHEMBL2092543 0.73 TRPM8 (0.51) NPC1RAB9ANPSR1LMNAALDH1A1
SCHEMBL1037465 0.72 NPSR1 (0.41) NPC1RAB9ANPSR1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785662-B2 Anilide-based compounds for preserving wood and method of use thereof SDS BIOTECH K.K. (JP) 2014-07-22 US disclosed
US-20130059014-A1 PRESERVATIVE FOR PRESERVING WOOD AND METHOD FOR TREATING WOOD SDS BIOTECH K. K. (JP) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059014-A1 PRESERVATIVE FOR PRESERVING WOOD AND METHOD FOR TREATING WOOD ALKBH5, DCXR, AKR7A2 HPGD 1403/4885NPC1 3459/4885RAB9A 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.