SCHEMBL7967022

SCHEMBL7967022

CCCN(CCC)C(=O)c1ccc(C)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 2/20 0.64
EGFR P00533 2/20 0.60
ERBB2 P04626 2/20 0.60
TP53 P04637 1/20 0.55
HPGD P15428 5/20 0.53
GABRA1 P14867 1/20 0.51
GABRB2 P47870 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
HDAC1 Q13547 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 4/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964228 0.93 EGFR (0.59) MLYCDEGFRERBB2TP53HPGD
SCHEMBL9694832 0.92 MLYCD (0.72) MLYCDEGFRERBB2TP53HPGD
SCHEMBL23717073 0.90 MLYCD (0.54) MLYCDEGFRERBB2TP53HPGD
SCHEMBL10455765 0.89 EGFR (0.62) MLYCDEGFRERBB2HPGDHDAC1
SCHEMBL11752532 0.87 EGFR (0.56) MLYCDEGFRERBB2HPGDHDAC1
SCHEMBL13900629 0.86 MLYCD (0.54) MLYCDEGFRERBB2TP53HPGD
SCHEMBL27899698 0.85 EGFR (0.55) MLYCDEGFRERBB2HPGDHDAC1
SCHEMBL13911247 0.85 HDAC1 (0.66) HPGDNPC1RAB9AHDAC1HDAC6
SCHEMBL7456186 0.84 ALDH1A1 (0.46) MLYCDEGFRERBB2HPGDNPC1
SCHEMBL4489409 0.84 MLYCD (0.64) MLYCDEGFRERBB2TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229257-A Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof 中国药科大学 2023-12-15 CN disclosed
CN-109563180-B Modified conjugated diene polymer, method for producing same, rubber composition, and tire 旭化成株式会社 2022-01-07 CN disclosed
CN-107250172-B Modified conjugated diene polymer, method for producing same, and modified conjugated diene polymer composition 旭化成株式会社 2021-04-09 CN disclosed
WO-2020263187-A1 COMPOUNDS FOR TREATMENT OF EYE DISORDERS SINOPSEE THERAPEUTICS (SG) 2020-12-30 WO disclosed
WO-2020263186-A1 COMPOUNDS FOR TREATMENT OF CANCER SINOPSEE THERAPEUTICS (SG) 2020-12-30 WO disclosed
CN-109384982-B Modified conjugated diene polymer composition and tire 旭化成株式会社 2020-11-17 CN disclosed
EP-3041841-B1 TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF HOFFMANN LA ROCHE (CH) 2019-06-05 EP disclosed
EP-3357916-A1 BENZAMIDE DERIVATIVE CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) 2018-08-08 EP disclosed
EP-2565182-B1 NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE MITSUBISHI TANABE PHARMA CORP (JP) 2017-10-11 EP disclosed
EP-2631980-B1 NON-AQUEOUS ELECTROLYTE SOLUTION DAIKIN IND LTD (JP) 2017-10-11 EP disclosed
WO-2010010190-A1 NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES GALAPAGOS NV (BE) 2010-01-28 WO disclosed
CN-101135852-A Pattern forming material and method FUJIFILM CORP (JP) 2008-03-05 CN disclosed
EP-0548155-B1 PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES MINNESOTA MINING & MFG (US) 1994-11-23 EP disclosed
EP-0548155-A1 PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES. MINNESOTA MINING & MFG (US) 1993-06-30 EP disclosed
EP-0492823-A2 Perfluorinated t-amino cyclic ethers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-01 EP disclosed
US-5108556-A Electrochemically fluorinating a tertiary thioamide precursor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-28 US disclosed
WO-1992005142-A1 PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-02 WO disclosed
US-4959209-A Use of N,N-diethyl-m-toluamide and/or the ethyl ester of 2-methyl-3-pentenoic acid as insect attractants INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1990-09-25 US disclosed
US-4880625-A Use of N,N-diethyl-m-toluamide and/or the ethyl ester of 2-methyl-3-pentenoic acid as insect attractants INTERNATIONAL FLAVORS & FRAGRANCES (US) 1989-11-14 US disclosed
US-4808403-A MIXING WITH POLYMER; ATTRACTING FLIES TO TRAPS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1989-02-28 US disclosed