Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965515 | 1.00 | PTGS2 (0.37) | PTGS2ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL6934036 | 1.00 | PTGS2 (0.37) | PTGS2ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL7983353 | 0.87 | CHRNA1 (0.42) | PTGS2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL6932927 | 0.87 | CHRNA1 (0.42) | PTGS2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7984718 | 0.87 | CHRNA1 (0.42) | PTGS2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL6026628 | 0.86 | MEN1 (0.37) | PTGS2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7966664 | 0.84 | HCAR2 (0.46) | PTGS2ALDH1A1HCAR3HCAR2TSHR | |
| SCHEMBL7030070 | 0.84 | HCAR2 (0.46) | PTGS2ALDH1A1HCAR3HCAR2TSHR | |
| SCHEMBL7969034 | 0.84 | ALDH1A1 (0.38) | PTGS2ALDH1A1KDM4ESMN1; SMN2HCAR3 | |
| SCHEMBL7956282 | 0.84 | HCAR2 (0.46) | PTGS2ALDH1A1HCAR3HCAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | claimed |