Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475241 | 0.88 | HTR7 (0.52) | HTR7KCNJ1SIGMAR1PLGPLAU | |
| SCHEMBL2263627 | 0.86 | MAPT (0.53) | HTR7KCNJ1MEN1ALDH1A1LMNA | |
| SCHEMBL15748141 | 0.82 | SIGMAR1 (0.53) | HTR7KCNJ1SIGMAR1P2RX7KCNH2 | |
| SCHEMBL29167527 | 0.81 | HTR7 (0.74) | HTR7MEN1ALDH1A1LMNACYP2D6 | |
| SCHEMBL2075531 | 0.81 | HTR7 (0.67) | HTR7PLGPLAUKRASMEN1 | |
| SCHEMBL12857291 | 0.81 | HTR7 (0.56) | HTR7PLGPLAU | |
| SCHEMBL15748176 | 0.80 | KMT2A (0.53) | HTR7DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL2264523 | 0.80 | HTR7 (0.65) | HTR7KRASMEN1ALDH1A1LMNA | |
| SCHEMBL23902704 | 0.80 | HTR7 (0.43) | HTR7KCNJ1PLGPLAUP2RX7 | |
| SCHEMBL30241361 | 0.80 | HTR7 (0.43) | HTR7KCNJ1PLGPLAUP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037034-A1 | E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |