Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70598 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| Hydrochloric Acid SCHEMBL28339344 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL20893876 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL8284047 | 0.74 | TDP1 (0.58) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL2221019 | 0.69 | TDP1 (0.67) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL19101990 | 0.69 | ALDH1A1 (0.58) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL29190994 | 0.69 | TDP1 (0.62) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL2419793 | 0.69 | ALDH1A1 (0.68) | SMN1; SMN2TDP1RAB9AGAAPKM | |
| SCHEMBL4731454 | 0.69 | — | — | |
| SCHEMBL9266730 | 0.68 | DAO (0.50) | SMN1; SMN2TDP1RAB9AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |