Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112722 | 0.77 | THRB (0.49) | PPARDTSPONPC1ALDH1A1LMNA | |
| SCHEMBL5228138 | 0.75 | PPARD (0.39) | PPARDMTNR1A | |
| SCHEMBL7202243 | 0.74 | MTNR1A (0.57) | NPC1ALDH1A1LMNAMAPTRECQL | |
| SCHEMBL4757354 | 0.73 | PPARD (0.54) | PPARD | |
| SCHEMBL5261924 | 0.73 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL5227858 | 0.72 | HTR2A (0.48) | PPARD | |
| SCHEMBL5227643 | 0.72 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL5228877 | 0.71 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL5528547 | 0.70 | SMPD1 (0.45) | PPARDNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL5229040 | 0.69 | MTNR1A (0.47) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |