Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914211 | 0.79 | TDP1 (0.42) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL29115594 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL21101392 | 0.79 | TDP1 (0.42) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL18913867 | 0.79 | TDP1 (0.42) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL1784947 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL30231620 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL29115592 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL1784949 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL16491484 | 0.78 | TDP1 (0.45) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL12017716 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |