Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914211 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL18913867 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL838767 | 0.80 | — | — | |
| SCHEMBL839985 | 0.80 | — | — | |
| SCHEMBL838766 | 0.80 | — | — | |
| SCHEMBL16491484 | 0.80 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL7967647 | 0.79 | ALDH1A1 (0.56) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL8627037 | 0.78 | PGK1 (0.46) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL16491485 | 0.77 | TDP1 (0.39) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL6049935 | 0.77 | ALOX15 (0.43) | ALDH1A1LMNAHSD17B10SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498368-A1 | ALIPHATIC ZR-, HF-, AND LN-BASED INORGANIC-ORGANIC HYBRID SOLID MOF MATERIALS, METHODS FOR PREPARING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-06-19 | — | — | EP | disclosed |