Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 3/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 2/20 | 0.33 |
| ▸ | CDC25C | P30307 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686787 | 0.75 | APEX1 (0.33) | — | |
| SCHEMBL9542709 | 0.72 | CES2 (0.40) | MAPTPTPN1CDC25BDUSP3ACP1 | |
| SCHEMBL13646793 | 0.71 | PTPN1 (0.34) | MAPTPTPN1CDC25BDUSP3ACP1 | |
| SCHEMBL13778159 | 0.71 | LMNA (0.55) | MAPTRECQLTDP1LMNAL3MBTL1 | |
| SCHEMBL13778139 | 0.71 | MAPT (0.38) | MAPTLMNAL3MBTL1 | |
| SCHEMBL13523341 | 0.67 | PTPN1 (0.35) | MAPTPTPN1CDC25BDUSP3ACP1 | |
| SCHEMBL13176951 | 0.67 | PTPN1 (0.36) | MAPTPTPN1CDC25BDUSP3ACP1 | |
| SCHEMBL15962403 | 0.67 | PTPN1 (0.36) | MAPTPTPN1CDC25BDUSP3ACP1 | |
| SCHEMBL736870 | 0.66 | — | — | |
| SCHEMBL4907108 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |