Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898319 | 0.94 | ALDH1A1 (0.50) | TRPV1 | |
| SCHEMBL1109704 | 0.92 | LPAR1 (0.49) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| SCHEMBL8678775 | 0.92 | LPAR1 (0.49) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| Ethylene SCHEMBL990189 | 0.90 | LPAR1 (0.53) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| Ethylene SCHEMBL28642010 | 0.90 | LPAR1 (0.53) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| Ethylene SCHEMBL990193 | 0.90 | LPAR1 (0.53) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| SCHEMBL24398977 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| SCHEMBL11576564 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| SCHEMBL2901529 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2FAAHTRPV1 | |
| SCHEMBL44028 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443130-B1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NAT RECH SCIENT (FR) | 2016-08-03 | — | — | EP | claimed |
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | claimed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | claimed |
| EP-2443130-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | Centre National de la Recherche Scientifique (FR) | 2012-04-25 | — | — | EP | claimed |
| EP-2270021-A1 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | Centre National de la Recherche Scientifique (FR) | 2011-01-05 | — | — | EP | claimed |
| WO-2010146127-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-12-23 | — | — | WO | claimed |
| WO-2023214017-A1 | CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER | VIROVET NV (BE) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023147478-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION | METASTX, LLC (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-2443130-B1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NAT RECH SCIENT (FR) | 2016-08-03 | — | — | EP | disclosed |
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-09-05 | — | — | US | disclosed |
| EP-2616474-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | Centre National De La Recherche Scientifique (FR) | 2013-07-24 | — | — | EP | disclosed |
| US-20130018018-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | Epiphany Biosciences ,Inc. (US) | 2013-01-17 | — | — | US | disclosed |
| US-20030227006-A1 | Organic based thermal stabilizers and heat stabilized polymer compositions | PMC CINCINNATI, INC. | 2003-12-11 | — | — | US | disclosed |
| EP-1342749-A2 | Organic based thermal stabilizers and heat stabilized polymer compositions | ROHM AND HAAS COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20030158311-A1 | Stabilized halogen-containing polymer composition | PMC CINCINNATI, INC. | 2003-08-21 | — | — | US | disclosed |
| EP-1318169-A2 | Stabilized halogen-containing polymer composition | ROHM AND HAAS COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-0459705-B1 | Surface-active Organopolysiloxanes | SHINETSU CHEMICAL CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5104998-A | ORGANOPOLYSILOXANE MODIFIED WITH POLYETHER AND HIGHER APLIPHATIC ETHER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0459705-A2 | Surface-active Organopolysiloxanes | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018018-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | PNP, TYMP, ENTPD5 | LPAR1 2041/4885LPAR3 2505/4885LPAR2 2605/4885 |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | PNP, PHPT1, TYMP | LPAR1 3954/4885LPAR3 3914/4885LPAR2 4205/4885 |
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | PNP, TYMP, EIF2AK2 | LPAR1 2832/4885LPAR3 3529/4885LPAR2 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.