Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995738 | 0.88 | DTYMK (0.39) | — | |
| SCHEMBL6990220 | 0.88 | CHRM1 (0.49) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| Maleic Acid SCHEMBL7669315 | 0.86 | CHRM1 (0.43) | MEN1KMT2AMAPTCHRM2CHRM4 | |
| SCHEMBL7002700 | 0.85 | CHRM1 (0.38) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL6990191 | 0.85 | CHRM1 (0.39) | CHRM1HRH1 | |
| SCHEMBL6993039 | 0.84 | DRD2 (0.47) | MEN1KMT2AKDM4EMAPTCHRM2 | |
| SCHEMBL6999455 | 0.84 | CHRM1 (0.46) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8123379 | 0.84 | HTR1A (0.37) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| Maleic Acid SCHEMBL7665213 | 0.84 | HTR2A (0.34) | MEN1KMT2AKDM4EMAPTCHRM2 | |
| Maleic Acid SCHEMBL7666685 | 0.84 | HRH4 (0.43) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271225-B1 | PSYCHOLOGICAL DISORDERS | WELFIDE CORPORATION (JP) | 2001-08-07 | — | — | US | disclosed |