Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL8203386 | 0.95 | HTR6 (0.52) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL4640457 | 0.95 | HTR6 (0.52) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL152444 | 0.95 | HTR6 (0.52) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| Methane SCHEMBL29092261 | 0.92 | HTR6 (0.50) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL7762376 | 0.86 | HTR6 (0.64) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| Methylene Chloride SCHEMBL9301312 | 0.86 | ALDH1A1 (0.46) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL28231295 | 0.84 | HTR6 (0.42) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL28108578 | 0.84 | HTR6 (0.42) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL28227130 | 0.84 | HTR6 (0.42) | HTR6ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL14354527 | 0.81 | ALDH1A1 (0.50) | HTR6ALDH1A1CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274297-B1 | Photothermographic recording material with in-situ and ex-situ photosensitive silver halide and a substantially light-insensitive organic salt | AGFA-GEVAERT (BE) | 2001-08-14 | — | — | US | disclosed |