Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10491107 | 0.76 | MAPT (0.46) | TP53MAPTTHRBNR3C2ALDH1A1 | |
| SCHEMBL9693069 | 0.76 | GRM7 (0.37) | — | |
| SCHEMBL9843624 | 0.76 | MAPT (0.43) | TP53MAPTTHRBNR3C2ALDH1A1 | |
| SCHEMBL4049030 | 0.75 | MMP12 (0.54) | TP53MAPTTHRBNR3C2ALDH1A1 | |
| SCHEMBL9342748 | 0.75 | RAF1 (0.40) | TP53MAPTTHRBNR3C2ALDH1A1 | |
| SCHEMBL9837061 | 0.75 | MAPT (0.39) | TP53MAPTTHRBNR3C2KMT2A | |
| SCHEMBL7556723 | 0.75 | MMP12 (0.46) | TP53MAPTTHRBNR3C2ALDH1A1 | |
| SCHEMBL9642306 | 0.74 | GRM7 (0.38) | — | |
| SCHEMBL9599303 | 0.74 | NR3C2 (0.38) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8878643 | 0.74 | TRPV1 (0.40) | TP53MAPTTHRBNR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63068587-A | — | — | None | — | — | JP | disclosed |
| US-6294503-B1 | HERBICIDAL COMPOSITIONS CONTAINING HETEROCYCLES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0263299-B1 | BENZOXAZINES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| US-4804394-A | Benzoxazines and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0263299-A1 | Benzoxazines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-04-13 | — | — | EP | disclosed |
| JP-S6368587-A | TETRAHYDROPHTHALIMIDES AND HERBICIDE | NIPPON TOKUSHU NOYAKU SEIZO KK | 1988-03-28 | — | — | JP | disclosed |