Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968234 | 1.00 | ABCB1 (0.51) | ABCB1ALDH1A1GLATP53GAA | |
| SCHEMBL7968230 | 1.00 | ABCB1 (0.51) | ABCB1ALDH1A1GLATP53GAA | |
| SCHEMBL7754055 | 0.84 | ALDH1A1 (0.54) | ABCB1ALDH1A1GLATDP1 | |
| SCHEMBL11217801 | 0.83 | ABCB1 (0.49) | ABCB1ALDH1A1GLASRCTGFBR1 | |
| SCHEMBL10734017 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GLATP53TDP1 | |
| SCHEMBL11483765 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GLATP53NPSR1TDP1 | |
| SCHEMBL4221973 | 0.81 | MAPT (0.47) | ALDH1A1GLATP53GAANPSR1 | |
| SCHEMBL3897600 | 0.80 | SRC (0.78) | SRCTGFBR1 | |
| SCHEMBL7177104 | 0.80 | ABCB1 (0.61) | ABCB1TP53GAAPTGDR2SRC | |
| SCHEMBL21668247 | 0.80 | TDP1 (0.53) | ALDH1A1GLATP53GAASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |