Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.64 |
| ▸ | F10 | P00742 | 11/20 | 0.64 |
| ▸ | PLG | P00747 | 7/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977870 | 0.84 | F2 (0.56) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7967842 | 0.82 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL4442315 | 0.79 | F2 (0.59) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL4442309 | 0.79 | F2 (0.59) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7413176 | 0.79 | F2 (0.40) | F2F10PLGITKSCN7A | |
| SCHEMBL7980030 | 0.78 | F2 (1.00) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7424485 | 0.78 | F2 (0.98) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7982042 | 0.77 | F2 (0.98) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426210 | 0.76 | F2 (0.46) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7978111 | 0.75 | F2 (0.44) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |