SCHEMBL7968296

SCHEMBL7968296

C=CCCn1nnn(C(=O)N(c2ccccc2)C(C)C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.35
TRPM8 Q7Z2W7 2/20 0.35
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
POLB P06746 1/20 0.33
MLYCD O95822 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977970 0.88 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL9620447 0.85 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8690403 0.84 ALDH1A1 (0.49) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL9620586 0.83 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL9620371 0.83 ALDH1A1 (0.46) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8550504 0.82 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8346740 0.81 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8546039 0.81 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8551992 0.79 MEN1 (0.35) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8550089 0.79 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6262275-B1 AS HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-07-17 US disclosed
US-6017853-A HERBICIDES; CHEMICAL INTERMEDIATES NIHON BAYER AGROCHEM K.K. (JP) 2000-01-25 US disclosed