SCHEMBL7968369

SCHEMBL7968369

N#C[CH]c1cccc(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
IDH1 O75874 1/20 0.32
IDH2 P48735 1/20 0.32
PSMB8 P28062 2/20 0.32
HTR3E A5X5Y0 2/20 0.31
HTR3B O95264 2/20 0.31
HTR3A P46098 2/20 0.31
HTR3D Q70Z44 2/20 0.31
HTR3C Q8WXA8 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7427498 0.80 NFE2L2 (0.45) NFE2L2L3MBTL1CYP3A4TSHRIDH1
SCHEMBL7427505 0.80 NFE2L2 (0.45) NFE2L2L3MBTL1CYP3A4TSHRIDH1
SCHEMBL31290604 0.71
SCHEMBL22579286 0.71
SCHEMBL1989599 0.71
SCHEMBL864373 0.71
SCHEMBL29953522 0.71
SCHEMBL22392916 0.71
SCHEMBL8616371 0.71
SCHEMBL10547338 0.71 L3MBTL1 (0.41) L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed