⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501750 | 0.85 | — | — | |
| SCHEMBL7291290 | 0.81 | HCAR2 (0.63) | — | |
| SCHEMBL448454 | 0.81 | HCAR2 (0.82) | — | |
| SCHEMBL322228 | 0.81 | HCAR2 (0.82) | — | |
| SCHEMBL448456 | 0.81 | HCAR2 (0.82) | — | |
| SCHEMBL9563109 | 0.81 | HCAR2 (0.60) | — | |
| SCHEMBL1580026 | 0.80 | — | — | |
| SCHEMBL1003104 | 0.79 | — | — | |
| SCHEMBL4934756 | 0.79 | HCAR2 (0.78) | — | |
| Hydrochloric Acid SCHEMBL28061109 | 0.79 | HCAR2 (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878193-B | Bicyclic gamma-amino acid derivatives | DAIICHI SANKYO CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-103483169-A | Bicyclic gamma-amino acid derivative | DAIICHI SANKYO CO LTD | 2014-01-01 | — | — | CN | disclosed |
| CN-102143946-A | Calcium channel modulators and uses thereof | LECTUS THERAPEUTICS LTD | 2011-08-03 | — | — | CN | disclosed |
| CN-101878193-A | Bicyclic gamma-amino acid derivatives | DAIICHI SANKYO CO LTD | 2010-11-03 | — | — | CN | disclosed |
| CN-101233108-A | Cyclic amine derivative having substituted alkyl group | DAIICHI SANKYO CO LTD (JP) | 2008-07-30 | — | — | CN | disclosed |
| CN-1328278-C | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2007-07-25 | — | — | CN | disclosed |
| CN-1910151-A | Cyclic amine derivative with heteroaryl ring | SANKYO CO (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1294129-C | Heteraryl-substituted porrole derivatives, their prep. and therapeutic use | SANKYO CO (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1886386-A | Phenylene derivative having tetrazole ring or thiazolidinedione ring | SANKYO CO (JP) | 2006-12-27 | — | — | CN | disclosed |
| CN-1289498-C | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 2006-12-13 | — | — | CN | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| CN-1265661-A | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| CN-1039642-C | Derivative of hexahydronaphthalene ester, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-09-02 | — | — | CN | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |
| CN-1172807-A | Neuraminic acid derivatives, their preparation and their medical use | SANKYO CO (JP) | 1998-02-11 | — | — | CN | disclosed |
| CN-1169986-A | 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives | CIBA GEIGY AG (CH) | 1998-01-14 | — | — | CN | disclosed |
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| CN-1098099-A | The hexahydro naphthalene ester derivative, their preparation and their treatment are used | SANKYO CO (JP) | 1995-02-01 | — | — | CN | disclosed |
| CN-1094707-A | Hexahydro-naphthalene ester derivative, their preparation and their application aspect treatment | SANKYO CO (JP) | 1994-11-09 | — | — | CN | disclosed |
| CN-1032786-A | N-acyl amino acid derivative and uses thereof | BANYU PHARMA CO LTD (JP) | 1989-05-10 | — | — | CN | disclosed |