Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421338 | 0.84 | ATM (0.74) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL8998064 | 0.84 | HCAR2 (0.55) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL448456 | 0.83 | HCAR2 (0.82) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL322228 | 0.83 | HCAR2 (0.82) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL448454 | 0.83 | HCAR2 (0.82) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL1003104 | 0.81 | — | — | |
| SCHEMBL7968445 | 0.81 | — | — | |
| SCHEMBL4934756 | 0.81 | HCAR2 (0.78) | HCAR2ATMTSHRHPGDAPP | |
| Hydrochloric Acid SCHEMBL28061109 | 0.81 | HCAR2 (0.78) | HCAR2ATMTSHRHPGDAPP | |
| SCHEMBL126841 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | disclosed |
| US-4767847-A | Nobamycin its analogs and process therefore | THE UPJOHN COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| US-4439602-A | Nogalamycin derivatives | THE UPJOHN COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4318790-A | Photochemical process for preparing N-demethyl-derivatives of nogalamycin | THE UPJOHN COMPANY (US) | 1982-03-09 | — | — | US | disclosed |