Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978124 | 1.00 | FFAR1 (0.52) | FFAR1ALDH1A1LMNASMN1; SMN2PPARG | |
| SCHEMBL7968507 | 1.00 | FFAR1 (0.52) | FFAR1ALDH1A1LMNASMN1; SMN2PPARG | |
| SCHEMBL3435628 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL4060044 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29512894 | 0.82 | CUL4A (0.49) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7978483 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7981185 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29512840 | 0.80 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1350897 | 0.79 | POLB (0.48) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2561960 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0987266-A1 | BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |