SCHEMBL7968624

SCHEMBL7968624

C=C(C)C(=O)OCC1CO1.C=C(C=CC(=O)O)C(=O)OCC

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
HCAR2 Q8TDS4 1/20 0.37
CYP3A4 P08684 2/20 0.36
TP53 P04637 1/20 0.36
THRB P10828 1/20 0.35
MGLL Q99685 2/20 0.33
TSHR P16473 4/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
GLO1 Q04760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL10696396 0.89 ALDH1A1 (0.81) ALDH1A1CYP3A4TP53THRBMGLL
SCHEMBL7973778 0.88 ALDH1A1 (0.66) ALDH1A1HCAR2CYP3A4TP53MGLL
Ethyl Fumarate SCHEMBL10773206 0.88 ALDH1A1 (0.66) ALDH1A1HCAR2CYP3A4TP53THRB
SCHEMBL7968534 0.88 ALDH1A1 (0.58) ALDH1A1HCAR2CYP3A4TP53THRB
SCHEMBL6662709 0.86 ALDH1A1 (0.86) ALDH1A1CYP3A4TP53THRBTSHR
SCHEMBL7968471 0.86 ALDH1A1 (0.44) ALDH1A1HCAR2CYP3A4TP53MGLL
Ethylene SCHEMBL20476767 0.85 ALDH1A1 (0.83) ALDH1A1CYP3A4TP53THRBMGLL
SCHEMBL7971611 0.84 ALDH1A1 (0.59) ALDH1A1HCAR2CYP3A4TP53THRB
Maleic Acid SCHEMBL11164489 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4TP53MGLLTSHR
SCHEMBL10894843 0.83 ALDH1A1 (0.54) ALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6180691-B1 MIXING AN INK VEHICLE, A COLORANT AND A LATEX CONTAINING A POLYMER WITH EPOXY GROUPS, WHICH IS GENERATED BY POLYMERIZING A MIXTURE OF OLEFINIC MONOMERS AND AN UNSATURATED MONOMER CONTAINING EPOXIDE IN PRESENCE OF ANIONIC/NONIONIC XEROX CORPORATION 2001-01-30 US disclosed