Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11164489 | 0.94 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Crotonic Acid SCHEMBL10700197 | 0.92 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Crotonic Acid SCHEMBL28107064 | 0.92 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Crotonic Acid SCHEMBL28077456 | 0.91 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Acrylic Acid SCHEMBL527679 | 0.90 | ALDH1A1 (0.81) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Acrylic Acid SCHEMBL28547922 | 0.90 | ALDH1A1 (0.81) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Ethyl Fumarate SCHEMBL10773206 | 0.90 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TP53MGLLTHRB | |
| SCHEMBL7973778 | 0.90 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Acetic Acid SCHEMBL866942 | 0.90 | ALDH1A1 (0.93) | ALDH1A1CYP3A4TP53MGLLTSHR | |
| Bicarbonate SCHEMBL5168901 | 0.90 | ALDH1A1 (0.93) | ALDH1A1CYP3A4TP53MGLLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289898-A2 | ADDITIVE FOR ASPHALT AND METHOD FOR PRODUCING AN ADDITIVE AND AN ASPHALT USING SUCH AN ADDITIVE | EcoPals GmbH (DE) | 2023-12-13 | — | — | EP | claimed |
| CN-110303612-A | The manufacturing device and manufacturing method of composite resin composition | 松下电器产业株式会社 | 2019-10-08 | — | — | CN | disclosed |
| CN-110272584-A | Fiber composite resin combination and its manufacturing method | 松下电器产业株式会社 | 2019-09-24 | — | — | CN | disclosed |
| CN-109762244-A | COMPOSITE RESIN MOLDED ARTICLE | 松下电器产业株式会社 | 2019-05-17 | — | — | CN | disclosed |
| CN-107811887-A | The manufacture method of cosmetic and cosmetic | 信越化学工业株式会社 | 2018-03-20 | — | — | CN | disclosed |
| EP-0264834-A1 | Electrodeposition coating composition | Nippon Paint Co., Ltd. (JP) | 1988-04-27 | — | — | EP | disclosed |