Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968877 | 0.91 | EBP (0.41) | EBPSIGMAR1CYP3A4CYP2D6TDP1 | |
| SCHEMBL7965756 | 0.91 | EBP (0.43) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7965668 | 0.89 | EBP (0.43) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7971946 | 0.89 | EBP (0.43) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7968651 | 0.88 | EBP (0.39) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7968642 | 0.87 | EBP (0.46) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7956606 | 0.84 | SIGMAR1 (0.47) | EBPSIGMAR1CYP3A4CYP2D6TDP1 | |
| SCHEMBL7971971 | 0.84 | L3MBTL1 (0.38) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7968543 | 0.84 | EBP (0.36) | EBPSIGMAR1CYP3A4CYP2D6AR | |
| SCHEMBL7966651 | 0.84 | EBP (0.39) | EBPSIGMAR1CYP3A4CYP2D6AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |