Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970183 | 0.80 | TRPC3 (0.48) | KMT2AALDH1A1KDM4EMEN1ESRRG | |
| SCHEMBL7968924 | 0.78 | DPP4 (0.43) | DPP4DPP9DPP7DPP8KMT2A | |
| SCHEMBL7955781 | 0.78 | DPP4 (0.43) | DPP4DPP9DPP7DPP8KMT2A | |
| Hydrochloric Acid SCHEMBL7965026 | 0.78 | TRPC3 (0.47) | KMT2AALDH1A1KDM4EMEN1ESRRG | |
| Hydrochloric Acid SCHEMBL7965029 | 0.78 | TRPC3 (0.47) | KMT2AALDH1A1KDM4EMEN1ESRRG | |
| SCHEMBL15422012 | 0.78 | CHRM1 (0.49) | DPP4DPP9DPP7DPP8KMT2A | |
| Hydrochloric Acid SCHEMBL2146257 | 0.77 | CHRM1 (0.47) | DPP4DPP9DPP7DPP8KMT2A | |
| SCHEMBL1334012 | 0.74 | KMT2A (0.48) | KMT2AALDH1A1KDM4EPARP10NPC1 | |
| SCHEMBL12124068 | 0.74 | KMT2A (0.48) | KMT2AALDH1A1KDM4EPARP10NPC1 | |
| SCHEMBL8150019 | 0.73 | ALDH1A1 (0.41) | DPP4DPP9DPP8KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | claimed |
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |