Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965668 | 0.91 | EBP (0.43) | EBPSIGMAR1CNR1CNR2NPSR1 | |
| SCHEMBL7968877 | 0.89 | EBP (0.41) | EBPSIGMAR1NPSR1MEN1KMT2A | |
| SCHEMBL7966573 | 0.89 | SIGMAR1 (0.41) | EBPSIGMAR1CNR1MEN1KMT2A | |
| SCHEMBL7965402 | 0.89 | EBP (0.41) | EBPSIGMAR1NPSR1MEN1KMT2A | |
| SCHEMBL7966011 | 0.87 | EBP (0.43) | EBPSIGMAR1CNR1CNR2MEN1 | |
| SCHEMBL7971832 | 0.83 | SIGMAR1 (0.45) | EBPSIGMAR1CNR1CNR2NPSR1 | |
| SCHEMBL7968615 | 0.82 | EBP (0.46) | EBPSIGMAR1CNR1CNR2NPSR1 | |
| SCHEMBL7969091 | 0.82 | SIGMAR1 (0.47) | EBPSIGMAR1NPSR1MEN1KMT2A | |
| SCHEMBL7968979 | 0.81 | SIGMAR1 (0.54) | EBPSIGMAR1CNR1CNR2NPSR1 | |
| SCHEMBL7968860 | 0.81 | SIGMAR1 (0.43) | EBPSIGMAR1CNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |
| US-5451604-A | Useful in organ transplant surgery | G. D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | disclosed |