SCHEMBL7969024

SCHEMBL7969024

CNCC(C)Cc1ccc(C(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
IDO1 P14902 2/20 0.42
ACACB O00763 2/20 0.41
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HTR1A P08908 1/20 0.37
THPO P40225 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9883275 0.84 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3IDO1ACACB
SCHEMBL15314153 0.80 TRPA1 (0.48) SLC6A2SLC6A4IDO1KMT2ATAAR1
SCHEMBL7956903 0.79 TAAR1 (0.57) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL17992755 0.79 TAAR1 (0.57) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL15314132 0.77 SLC6A4 (0.56) CYP2D6SLC6A4IDO1ACACBKMT2A
SCHEMBL7966471 0.77 TP53 (0.51) KCNH2ACACB
SCHEMBL18570895 0.77 IDO1 (0.47) SLC6A2SLC6A3IDO1ACACBL3MBTL1
SCHEMBL13995832 0.77 ACACB (0.42) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL1219827 0.75 ESR1 (0.45) IDO1ACACBESR1ESR2BLM
SCHEMBL20610522 0.75 ESR1 (0.45) IDO1ACACBESR1ESR2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271385-B1 FUNGICIDES (SUCH AS THOSE FOR USE IN FARMING AND HORTICULTURE). KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-07 US disclosed
EP-1020441-A1 N-HETEROCYCLIC METHYLPROPYLAMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND GERMICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-07-19 EP disclosed