Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931739 | 0.97 | POLB (0.44) | POLBCASP6NCF1L3MBTL1TDP1 | |
| SCHEMBL7222571 | 0.88 | POLB (0.42) | POLBCASP6L3MBTL1TDP1CYP1A2 | |
| SCHEMBL7922026 | 0.88 | HTT (0.39) | NCF1L3MBTL1THRAMEN1KMT2A | |
| SCHEMBL7969081 | 0.87 | NCF1 (0.40) | POLBCASP6NCF1L3MBTL1TDP1 | |
| SCHEMBL6344981 | 0.87 | L3MBTL1 (0.38) | NCF1L3MBTL1TDP1CYP1A2CYP2D6 | |
| SCHEMBL6344107 | 0.87 | L3MBTL1 (0.47) | POLBL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL7922019 | 0.85 | MAPT (0.45) | POLBCASP6L3MBTL1MEN1KMT2A | |
| SCHEMBL6343600 | 0.85 | KDM4E (0.44) | POLBCASP6L3MBTL1TDP1CYP1A2 | |
| SCHEMBL7929514 | 0.84 | POLB (0.43) | POLBCASP6L3MBTL1TDP1CYP1A2 | |
| SCHEMBL7931735 | 0.84 | L3MBTL1 (0.44) | POLBCASP6NCF1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |