SCHEMBL7969111

SCHEMBL7969111

Nc1ccc(-c2cccc(Cl)c2)cc1Cl

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.68
TSHR P16473 2/20 0.68
ALDH1A1 P00352 2/20 0.68
MAPK1 P28482 1/20 0.68
PGR P06401 1/20 0.57
ESR2 Q92731 2/20 0.57
TAAR1 Q96RJ0 2/20 0.55
ALOX5 P09917 1/20 0.52
MAOB P27338 2/20 0.50
BACE1 P56817 1/20 0.50
JAK2 O60674 1/20 0.49
MAP4K4 O95819 3/20 0.47
ADORA2A P29274 2/20 0.45
ADORA1 P30542 2/20 0.45
ADORA2B P29275 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL11773808 0.98 CYP3A4 (0.65) CYP3A4TSHRALDH1A1MAPK1PGR
SCHEMBL49382 0.84 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL29365311 0.84 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL8872306 0.84 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL30618020 0.83 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL7142676 0.83 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL22567867 0.83 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL30618019 0.83 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL23137319 0.82 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL864592 0.82 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248197-B1 Method for producing a shaped multifilament, non-thermoplastic, elastomeric yarn E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-19 US disclosed