SCHEMBL7142676

SCHEMBL7142676

Nc1ccc(-c2ccccc2)cc1Cl

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.74
TSHR P16473 3/20 0.74
ALDH1A1 P00352 3/20 0.74
MAPK1 P28482 1/20 0.74
ESR2 Q92731 2/20 0.67
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
HSP90AA1 P07900 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
HTT P42858 1/20 0.52
IKBKB O14920 1/20 0.50
MAOA P21397 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22567867 1.00 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL30618020 1.00 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL30618019 1.00 CYP3A4 (0.74) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL27792469 0.98 CYP3A4 (0.78) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL23137319 0.91 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2
1,2-Dichlorobenzene SCHEMBL11041680 0.88 TSHR (0.77) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL8872306 0.88 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL29365311 0.88 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL49382 0.88 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL29368557 0.85 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100475-A1 COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME キヤノン株式会社 2025-05-15 WO disclosed
US-12219869-B2 Composition for organic optoelectronic device, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2025-02-04 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
CN-116987089-A Compound for organic optoelectronic device, composition for organic optoelectronic device, and display device 三星SDI株式会社 2023-11-03 CN disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
WO-2023061998-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-20 WO disclosed
US-11581497-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
US-5977301-A AUTOMATED AND EFFICIENT SYNTHESIS BY REACTING SOLID SUPPORT BOUND AMINE WITH AN ACYLATING SUBMONOMER TO PRODUCE A SOLID SUPPORT-BOUND AMIDE WHICH CAN BE FURTHER REACTED; ONLY REACTIVE SIDE CHAINS NEED PROTECTED CHIRON CORPORATION (US) 1999-11-02 US disclosed
US-5877278-A SOLID PHASE SYNTHESIS USING TWO SUBMONOMERS-AN ACYLATING AGENT, E.G. A HALOACETIC ACID, AND A PRIMARY AMINE; CYCLIZATION TO PRODUCE MIMETICS OF DRUGS; ELIMINATION OF THE NECESSITY OF PROTECTION GROUPS CHIRON CORPORATION (US) 1999-03-02 US disclosed
US-5831005-A ACYLATION, NUCLEOPHILIC DISPLACEMENT CYCLES CHIRON CORPORATION (US) 1998-11-03 US disclosed
EP-0671928-A4 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS. CHIRON CORP (US) 1997-04-23 EP disclosed
US-5480871-A TREATMENT OF BENIGN PROSTATIC HYPERPLASIA CHIRON CORPORATION (US) 1996-01-02 US disclosed
EP-0671928-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1995-09-20 EP disclosed
US-5447916-A Hypotensive agents CHIRON CORPORATION (US) 1995-09-05 US disclosed
WO-1995004072-A1 PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS CHIRON CORPORATION (US) 1995-02-09 WO disclosed
WO-1994006451-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1994-03-31 WO disclosed
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12219869-B2 Composition for organic optoelectronic device, organic optoelectronic device, and display device OR10J3, OCIAD2, OCIAD1 CYP3A4 515/4885TSHR 3937/4885ALDH1A1 270/4885
US-20230151026-A1 MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION DDT, EPCAM, SLC18A3 CYP3A4 366/4885TSHR 4048/4885ALDH1A1 512/4885
US-11581497-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM CYP3A4 1201/4885TSHR 4759/4885ALDH1A1 504/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 CYP3A4 2522/4885TSHR 3272/4885ALDH1A1 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.