Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.44 |
| ▸ | ITGAV | P06756 | 16/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982799 | 0.90 | ITGB3 (0.48) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7980556 | 0.86 | ITGB3 (0.42) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7980575 | 0.84 | ITGB3 (0.39) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969114 | 0.84 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL7985895 | 0.82 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7349050 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982789 | 0.80 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982795 | 0.80 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982197 | 0.79 | ITGB3 (0.56) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7982415 | 0.78 | ITGB3 (0.42) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |