Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.48 |
| ▸ | ITGAV | P06756 | 15/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969121 | 0.90 | ITGB3 (0.44) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7969114 | 0.89 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982789 | 0.85 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL7357201 | 0.84 | ITGB3 (0.46) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7349050 | 0.84 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL7980535 | 0.82 | ITGB3 (0.43) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982197 | 0.82 | ITGB3 (0.56) | ITGB3ITGAVITGA2BEGLN2EGLN1 | |
| SCHEMBL7982161 | 0.80 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7985893 | 0.78 | ITGAV (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979200 | 0.76 | ITGB3 (0.44) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |