Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972246 | 0.73 | CYP1A2 (0.38) | SCN2AGRIN1GRIN2B | |
| SCHEMBL5545405 | 0.72 | KDM4E (0.45) | SCN10ASCN5AKCNH2SCN1ASCN9A | |
| SCHEMBL1230049 | 0.70 | SCN5A (0.48) | SCN10ASCN5AKCNH2SCN1ASCN9A | |
| SCHEMBL1742853 | 0.69 | CHRM5 (0.54) | SCN10ASCN5AKCNH2SCN1ASCN9A | |
| SCHEMBL454722 | 0.69 | AKR1C2 (0.42) | SCN5ASCN1ASCN2ACHRNA7NOTUM | |
| SCHEMBL7972131 | 0.69 | SCN2A (0.44) | SCN2ANOTUMIDO1NPY5R | |
| SCHEMBL255564 | 0.68 | CCR6 (0.50) | CHRNA7GRIN2BALOX5DHODH | |
| SCHEMBL20203802 | 0.67 | CYP1A2 (0.48) | SCN10ASCN5AKCNH2SCN1ASCN9A | |
| SCHEMBL28279859 | 0.66 | CHRNA7 (0.41) | SCN5ACHRNA7ALOX5NISCHIDO1 | |
| SCHEMBL28279876 | 0.66 | CHRNA7 (0.41) | SCN5ACHRNA7ALOX5NISCHIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |