Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972200 | 0.81 | KIF11 (0.40) | SCN2ADYRK1ADYRK2NOTUMKDM1A | |
| SCHEMBL7972246 | 0.76 | CYP1A2 (0.38) | SCN2AALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL6240438 | 0.74 | KDM1A (0.57) | SCN2ADYRK1ADYRK2CCNA2CDK2 | |
| SCHEMBL1967055 | 0.74 | SCN2A (0.44) | SCN2AIDO1HRH1HRH4ALDH1A1 | |
| SCHEMBL8307164 | 0.72 | RORB (0.44) | ALDH1A1MEN1HPGDKMT2AKDM4E | |
| SCHEMBL7958295 | 0.70 | HSD11B1 (0.39) | ALDH1A1CYP1A2CYP3A4TSHRHIF1A | |
| SCHEMBL457115 | 0.69 | MAOB (0.45) | SCN2ADYRK1ADYRK2CCNA2CDK2 | |
| SCHEMBL5106003 | 0.69 | MAPT (0.41) | SCN2ADYRK1ADYRK2CCNA2CDK2 | |
| SCHEMBL11158643 | 0.69 | CCNA2 (0.55) | SCN2ADYRK1ADYRK2CCNA2CDK2 | |
| SCHEMBL29678302 | 0.69 | TSHR (0.58) | SCN2AIDO1ALDH1A1TSHRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |