SCHEMBL7969261

SCHEMBL7969261

CCCCCNC(=O)c1cccc(Cl)n1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
LMNA P02545 1/20 0.54
NAAA Q02083 3/20 0.51
CNR1 P21554 2/20 0.50
KDM4E B2RXH2 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
EPHX1 P07099 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12468826 0.95 LMNA (0.55) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL30545065 0.88 HPGD (0.64) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL29913866 0.85 ALDH1A1 (0.57) HPGDMAPK1NPSR1LMNAKDM4E
SCHEMBL18157897 0.84 LMNA (0.68) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL12468996 0.83 CTSA (0.48) HPGDNPSR1LMNACNR1KDM4E
SCHEMBL31500520 0.82 LMNA (0.57) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL29216695 0.82 LMNA (0.61) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL9967794 0.82 HPGD (0.62) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL10867674 0.81 HPGD (0.58) HPGDMAPK1NPSR1LMNANAAA
SCHEMBL3503784 0.80 MAOB (0.56) HPGDLMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed