Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078962 | 0.71 | SMN1; SMN2 (0.53) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22809604 | 0.71 | CYP1A2 (0.48) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL22809557 | 0.70 | CYP1A2 (0.53) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7972466 | 0.70 | KCNN4 (0.43) | LMNASMN1; SMN2CYP1A2CYP2C19HPGD | |
| SCHEMBL6743790 | 0.69 | MRGPRX4 (0.71) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL12495523 | 0.69 | CYP2C9 (0.52) | LMNASMN1; SMN2CYP1A2GAAKMT2A | |
| SCHEMBL31568518 | 0.69 | MRGPRX4 (0.67) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8370602 | 0.69 | HIF1A (0.50) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL8370605 | 0.69 | HIF1A (0.50) | MRGPRX4LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7959238 | 0.69 | KCNN4 (0.44) | LMNACYP2C19POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313150-B1 | FOR CONTROLLING PHYTOPATHOGENIC FUNGI | SHIONOGI & CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0754672-B1 | GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5948819-A | α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it | SHIONOGI & CO., LTD (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0754672-A1 | GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |