Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274616 | 0.88 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8596687 | 0.85 | CA12 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3110696 | 0.83 | PDE4D (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9082411 | 0.83 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16275009 | 0.82 | SMN1; SMN2 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15170666 | 0.80 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1NPC1LMNA | |
| SCHEMBL18113761 | 0.79 | HSD17B10 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10177625 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ENPC1NPSR1 | |
| SCHEMBL843997 | 0.76 | ADORA3 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15155090 | 0.75 | ADORA3 (0.49) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2825533-B1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-9462809-B2 | Fungicidal pyrimidine compounds | BASF SE (DE) | 2016-10-11 | — | — | US | disclosed |
| US-20160221964-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2016-08-04 | — | — | US | disclosed |
| EP-3046915-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2016-07-27 | — | — | EP | disclosed |
| US-20150373980-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2015-12-31 | — | — | US | disclosed |
| WO-2015036058-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2015-03-19 | — | — | WO | disclosed |
| EP-2825533-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2015-01-21 | — | — | EP | disclosed |
| EP-2810944-A1 | HETEROCYCLIC COMPOUND HAVING ANTI-HIV ACTIVITY | Toyama Chemical Co., Ltd. (JP) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013135671-A9 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013135671-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2013-09-19 | — | — | WO | disclosed |
| US-5948819-A | α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it | SHIONOGI & CO., LTD (JP) | 1999-09-07 | — | — | US | disclosed |
| US-5852023-A | Cyclohexylamino and cycloalkoxy nitrogen heterocycles, processes for their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| CN-1179773-A | Cyclohexylamino and cyclohexylalkoxy nitrogen heterocycles, methods of preparing them and their use as pest-control agents and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-04-22 | — | — | CN | disclosed |
| EP-0817774-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-01-14 | — | — | EP | disclosed |
| CN-1145061-A | Alpha-substituted phenylacetic acid derivatives, their preparation and agricultural fungicides containing the same | SHIONOGI & CO (JP) | 1997-03-12 | — | — | CN | disclosed |
| EP-0754672-A1 | GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| WO-1996030345-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-10-03 | — | — | WO | disclosed |
| US-5519139-A | FUNGICIDES, INSTECTICIDES, MITICIDES | SHIONOGI & CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5439911-A | A potent fungicides, insecticides and miticides | SHIONOGI & CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0606011-A1 | Aminopyrimidine derivatives and their production and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150373980-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | DPM1, DPYD, TYMP | CA12 4717/4885CA1 4201/4885CA2 3669/4885 |
| US-20160221964-A1 | FUNGICIDAL PYRIMIDINE COMPOUNDS | DPM1, DPYD, TYMP | CA12 4698/4885CA1 3922/4885CA2 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.