Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.61 |
| ▸ | MAOA | P21397 | 10/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383666 | 0.91 | MAOB (0.62) | MAOBMAOAHRH3 | |
| SCHEMBL6171707 | 0.86 | MAOB (0.61) | MAOBMAOAHRH3 | |
| SCHEMBL4382609 | 0.84 | HRH3 (0.56) | MAOBMAOAHRH3 | |
| SCHEMBL10926632 | 0.79 | HRH3 (0.55) | MAOBMAOAHRH3 | |
| SCHEMBL4378238 | 0.78 | SMN1; SMN2 (0.50) | HRH3 | |
| SCHEMBL8574849 | 0.76 | MAOA (0.44) | MAOBMAOAHRH3 | |
| SCHEMBL4379604 | 0.75 | SMN1; SMN2 (0.47) | HRH3 | |
| SCHEMBL7698593 | 0.74 | MAOB (0.78) | MAOBMAOAHRH3 | |
| SCHEMBL948052 | 0.73 | MAOB (0.93) | MAOBMAOA | |
| SCHEMBL15839887 | 0.73 | MAOB (1.00) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265422-B1 | ANTICANCER AGENTS; CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |